A 54-year-old man with a history of coronary artery disease, hypertension, and hyperlipidemia presents for his annual physical exam. Despite maximal rosuvastatin and ezetimibe therapy, his LDL has decreased from 285 mg/dL to 140 mg/dL over six months but remains elevated. He expresses concern about his LDL levels. A medical student on rotation suggests considering alirocumab for further treatment. Which of the following best describes the mechanism of action of alirocumab?
