A 42-year-old woman visits her gynecologist for a routine check-up, expressing concern about her family history of ovarian and breast cancer. Her mother was diagnosed with ovarian cancer at age 58, and her maternal aunt developed breast cancer at age 50. Although she has no personal history of cancer or significant medical issues and is currently asymptomatic, she is worried about her own risk and seeks advice on preventive strategies. Which of the following is considered a major risk factor for ovarian cancer?