A 35-year-old man is admitted with complaints of headache, abdominal pain, and dark urine for three days. His labs show a platelet count of 20,000/µL, creatinine of 2.5 mg/dL, creatinine of 1.5 mg/dL and bilirubin of 3 mg/dL. A peripheral smear reveals fragmented red blood cells. He has no recent history of diarrhea but mentions starting a new medication, ticlopidine, two weeks ago.What is the most appropriate initial treatment for this patient?
