A 48-year-old man presents with a 3-month history of painful erections and a noticeable downward bend in his penis. He denies trauma but mentions the symptoms began after vigorous sexual activity. On exam, a tender plaque is felt on the ventral penile shaft. He is distressed about the condition and seeks treatment to halt progression. Which of the following treatments is most likely to reduce plaque size and improve curvature in the active phase of this condition?