Key Points  Adenosine Deaminase Deficiency, a form of Severe Combined Immunodeficiency (SCID), is a purine metabolic disorder caused by mutations in the ADA gene, resulting in immunodeficiency and its complications.  -It was first discovered in 1972 by American genetic scientist, Eloise Giblett. -In 1990, it was the first pathophysiologic condition to be treated by gene […]