A 14-year-old boy with Osgood-Schlatter disease is eager to return to playing soccer. He asks the physician how long it will take for his symptoms to resolve. Which of the following statements is the most appropriate response?
A 14-year-old female basketball player reports pain below her knee for 6 weeks, worse after games. She denies trauma but notes a tender bump at the tibial tuberosity. Her coach asks about treatment. Physical exam confirms pain with resisted knee extension and a prominent tibial tuberosity. She has no fever or systemic symptoms. Question: What is the most appropriate initial management for this patient’s condition?
A 12-year-old basketball player complains of pain below the knee that worsens with jumping and running. Examination shows localized swelling and tenderness over the tibial tubercle without joint effusion. Which of the following is the best initial management?
A 12-year-old male presents with a 2-month history of knee pain after starting track and field. His mother notes a bony prominence below his knee. Examination reveals tenderness at the tibial tuberosity, pain with squatting, and no joint effusion. His growth plates are open on X-ray, with fragmentation at the apophysis. Which of the following is the primary pathophysiological mechanism of this condition?
A 13-year-old boy who plays soccer five times a week presents with progressive anterior knee pain for the past two months. The pain worsens during running and jumping but improves with rest. Physical examination reveals tenderness and swelling over the tibial tuberosity. There is no effusion or instability. Which of the following is the most likely diagnosis?
Which of the following drugs, when given alongside omeprazole, could lead to increased serum levels due to omeprazole’s effect on CYP enzymes?
A patient on warfarin therapy is prescribed omeprazole for GERD. What is the primary concern regarding this combination?
Which of the following drugs might have its efficacy reduced when co-administered with omeprazole due to inhibition of CYP2C19?
A 52-year-old male presents to the emergency department with hematemesis and severe upper abdominal pain. He has a history of alcohol use disorder and was recently diagnosed with cirrhosis. On examination, he is hypotensive (BP: 90/60 mmHg) and tachycardic (HR: 110 bpm). Endoscopy reveals actively bleeding esophageal varices. Interventional radiology is consulted for embolization. Which of the following vessels is most likely involved in the blood supply contributing to the esophageal varices in this patient?
A 50-year-old man with a history of alcohol use disorder presents with severe hematemesis. He reports several episodes of retching prior to the bleeding. On examination, he is pale, hypotensive, and tachycardic. Endoscopy reveals a mucosal tear at the gastroesophageal junction with ongoing active bleeding. What is the most appropriate immediate intervention?
