A 2-month-old infant is brought to your clinic by her parents for a follow-up after abnormal newborn screening results. The baby appears healthy but has a musty body odor. The parents report she becomes irritable after feedings, which include formula and high-protein foods. A review of her newborn records reveals a positive test for phenylketonuria (PKU). The parents are concerned about potential complications of PKU, including its impact on her development and other organ systems, such as the heart. You explain that certain congenital heart defects are associated with PKU and discuss next steps in her management. Which of the following heart defects are common in patients with phenylketonuria?
