A 24 year-old Colombian male who was detained in the local immigration processing center was brought to your office by ICE officers for the evaluation of syphilis tests done as part of his immigration application. The RPR test and later FTA-ABS test came positive for syphilis. Through a translator, the patient explained that recently he got a fever, sore throat, wart-like lesions around his genitalia and rough, reddish brown spots on the bottom of his feet and on the palms of his hands. He also informed that many years ago, he received penicillin treatment for syphilis with no adverse complications. You diagnosed him with syphilis and started treatment with benzathine penicillin G. He was taken back to the detention center. Four hours later, the officers brought him back to your office because starting about two hours ago, the patient complained of fever as high as 107.6 F, chills, sweating, headache, nausea and vomiting, and muscle pains. His vital signs recorded were Temp = 102 F, BP = 110/80 mm Hg, RR = 24/minute, Pulse = 96/minute. Physical examination was unremarkable except for an anxious and distressful patient. Skin did not show any urticaria and wheels. Stat laboratory values showed elevated neutrophils but normal eosinophils. With rest, oral fluids, and acetaminophen, four hours later, the patient reported ‘I feel a lot better than when I came in’. His vital signs were Temp = 98.2 F, BP = 110/80 mmHg, RR = 18/minute; Pulse = 69/minute. Regarding this reaction which patient developed after starting the treatment, which of the following is true?
