A 25-year-old male presents with a history of exercise intolerance, muscle cramps, and fatigue during physical activity. He notes that after a brief rest, he is able to continue the activity with significantly less discomfort. Laboratory tests reveal elevated serum creatine kinase (CK) levels and myoglobinuria following exercise. Genetic testing confirms a diagnosis of Glycogen Storage Disease Type V (McArdle Disease). Which of the following best explains the patient’s ability to continue physical activity after a short rest?
