A 26-year-old female patient comes to your office for her annual physical examination. Concerned about ovarian cancer after reading that it is the leading cause of death among gynecologic malignancies in the United States, she requests additional testing “just to be safe.” Her medical history is reassuring: menarche at age 14, married with three children whom she breastfed, no family history of breast or ovarian cancer, and she has used oral contraceptives for two years followed by tubal ligation one month ago. She is asymptomatic and in good health overall, yet she insists on undergoing screening to rule out ovarian cancer. Question: Which of the following is an effective screening test or program for ovarian cancer in this asymptomatic, low-risk patient?
