A 32-year-old female presents to the clinic with complaints of fatigue, muscle weakness, and recurrent infections over the past few months. Laboratory tests reveal elevated levels of aspartate aminotransferase (AST) and alanine aminotransferase (ALT) in her blood, suggesting possible liver or muscle damage. Further investigation into her metabolic enzymes indicates a potential issue with an aminotransferase enzyme, which is known to catalyze a two-substrate, two-product (Bi-Bi) reaction. The medical team considers the enzyme kinetics involved to better understand the underlying mechanism and guide diagnostic and therapeutic decisions. Which of the following best describes the kinetic mechanism of the aminotransferase enzyme implicated in this patient’s condition?
