A 32-year-old male farmer presents to the emergency department with excessive salivation, difficulty breathing, and confusion. He reports spraying pesticides on his field earlier in the day. Approximately one hour after exposure, he begins experiencing profuse sweating, excessive tearing, nausea, and abdominal cramping. Over time, he develops significant muscle weakness and respiratory distress. Physical Examination: Vital Signs: BP: 90/60 mmHg HR: 50 bpm RR: 30/min Temp: 98.6°F SpO₂: 88% on room air General appearance: Confused and diaphoretic male, with respiratory distress. HEENT: Miosis (pinpoint pupils), excessive salivation, lacrimation. Chest: Bilateral wheezing with frothy secretions. Cardiovascular: Bradycardia with no murmurs. Abdomen: Hyperactive bowel sounds. Neurological: Muscle fasciculations in the arms and legs, generalized weakness, decreased responsiveness. What is the primary mechanism of action of this disorder ( organophosphate compounds) in the human body?
