A 32-year-old woman from Egypt presents with dysuria, hematuria, and a palpable pelvic mass. She has a history of recurrent urinary infections since childhood. Cystoscopy reveals a thickened bladder wall with granulomas, and histology shows carcinoma with calcified eggs. What is the primary pathological process initiated by Schistosoma haematobium that increases the risk of bladder carcinoma in this patient?
