A 32-year-old woman presents to the emergency room with chest pain localized under her right breast for the past two days. She also reports severe pain in her right lower leg, a constant headache, and blurry vision lasting over 12 hours. She denies fever, nausea, vomiting, or diarrhea. Her medications include a combination oral contraceptive for birth control and acetaminophen for headaches. Which of the following is a warning sign associated with her use of a combination oral contraceptive?