A 32-year-old woman presents to the gynecology clinic after an abnormal Pap smear result showing low-grade squamous intraepithelial lesions (LSIL). She has no history of prior cervical abnormalities and reports being sexually active with one partner. She has received three doses of the HPV vaccine and denies symptoms like abnormal vaginal bleeding, discharge, or pelvic pain. Colposcopy Findings: Acetowhite changes and mosaicism in the transformation zone Directed biopsies are taken for further evaluation She is counseled on possible outcomes and asks about the histological features of potential cervical cancers. Which of the following is a hallmark histological feature of squamous cell carcinoma of the cervix?