A 44-year-old Indian woman presents to the emergency room with complaints of right leg soreness and fatigue. The pain began two days ago following a long flight from South Africa. Her medical history includes diabetes, and she is recovering from a hysterectomy performed 10 days ago. She interrupted her post-surgical recovery for a family emergency. She smokes one pack of cigarettes daily. Physical Examination: Obese, afebrile, and anxious. Right lower leg swelling with a calf circumference 4 cm larger than the left leg. Collateral superficial veins present. Entire leg swollen with pitting edema. Tenderness increases with calf compression and dorsiflexion of the right foot with the knee extended (positive Homan’s sign). No redness of the leg. A lower extremity ultrasound confirmed the diagnosis of deep vein thrombosis (DVT). What is the most appropriate anticoagulation therapy for the management of deep vein thrombosis in this patient?
