A 52-year-old male with a history of hyperlipidemia presents with difficulty achieving and maintaining an erection for the past 6 months. He has no history of diabetes or hypertension but admits to a sedentary lifestyle and a high-fat diet. His lipid profile shows elevated LDL cholesterol and triglycerides. Which of the following mechanisms is most directly responsible for erectile dysfunction in this patient with dyslipidemia?
