Case Scenario: A 48-year-old male presents with burning epigastric pain, bloating, and nausea, which worsens after meals. He reports frequent acid reflux and has a history of gastritis. A urea breath test is performed and confirms the presence of Helicobacter pylori, a bacterium that survives in the stomach by neutralizing acid. The physician explains that a nickel-dependent enzyme plays a key role in this bacterial survival. Which of the following nickel-dependent enzymes is responsible for Helicobacter pylori’s ability to colonize the stomach?
