Patient Case: A 35-year-old male presents to the emergency department with severe abdominal pain, nausea, and vomiting. Laboratory tests reveal elevated levels of amylase and lipase, and imaging confirms acute pancreatitis. The physician explains that premature activation of digestive enzymes within the pancreas is likely causing tissue damage. Question: Which mechanism is most likely responsible for the tissue damage in this patient with acute pancreatitis?
