Which of the following organisms is associated with aplastic crisis seen in patients with sickle cell anemia? A.Coxsackie A virus B. Roseola virus C.Parvovirus B19 D.Epstein-Barr virus E. Human papillomavirus Correct Answer is C. Aplastic anemia (AA) is a rare life-threatening disorder characterized by pancytopenia and a hypocellular bone marrow. Parvovirus B19 can cause aplastic crisis in patients with sickle cell disease. Incorrect Answers: A.Coxsackie A virus causes hand,foot and mouth disease. B. Roseola virus (HHV-6) causes sixth disease, mostly in children. D.Epstein-Barr virus causes infectious mononucleosis. E. Human papilloma virus commonly causes skin or mucous membrane warts.
