Christina, a 55-year-old woman, presents to her primary care physician with a blood pressure reading of 150/90 mmHg. She has a history of hypertension but has not been consistently taking her medications. The physician discusses the importance of controlling blood pressure to reduce the risk of heart disease, stroke, and kidney disease. She is started on a diuretic to lower her blood pressure. She is educated about the potential side effects of the medication. She is advised to monitor her blood pressure at home and report any side effects to her doctor. Of the following, which diuretic is most commonly associated with development of gout?

A 54-year-old man presents to the clinic for a pre-employment physical examination. He has no complaints other than ‘occasional coughs and colds’. His only concern is elevated blood pressure for the last 4 weeks. He made some lifestyle changes including exercise, weight loss, smoking cessation and a low-salt diet. His temperature is 99 ⁰ F, heart rate is 72 beats per minute, respiratory rate is 14 breaths per minute, and blood pressure is 160/90 mm Hg. You prescribe hydrochlorothiazide to treat his hypertension. Of the following, which is the mechanism of action of this medication?

A 54-year-old man presents to the clinic for a pre-employment physical examination. He has no complaints other than ‘occasional coughs and colds’. His only concern is elevated blood pressure for the last 4 weeks. He made some lifestyle changes including exercise, weight loss, smoking cessation and a low-salt diet. His temperature is 99 ⁰ F, heart rate is 72 beats per minute, respiratory rate is 14 breaths per minute, and blood pressure is 160/90 mm Hg. You prescribe hydrochlorothiazide to treat his hypertension.What is the major site of action of this medication?

A 54-year-old man presents to the clinic for a pre-employment physical examination. He has no complaints other than ‘occasional coughs and colds’. His only concern is elevated blood pressure for the last 4 weeks. He made some lifestyle changes including exercise, weight loss, smoking cessation and a low-salt diet. His temperature is 99 ⁰ F, heart rate is 72 beats per minute, respiratory rate is 14 breaths per minute, and blood pressure is 160/90 mm Hg. You prescribe hydrochlorothiazide to treat his hypertension. Which of the following is true about this medication?

A 54-year-old man presents to the clinic for a pre-employment physical examination. He has no complaints other than ‘occasional coughs and colds’. His only concern is elevated blood pressure for the last 4 weeks. He made some lifestyle changes including exercise, weight loss, smoking cessation and a low-salt diet. His temperature is 99 ⁰ F, heart rate is 72 beats per minute, respiratory rate is 14 breaths per minute, and blood pressure is 160/90 mm Hg. You prescribe hydrochlorothiazide to treat his hypertension. Which of the following is an adverse effect of this medication?