Questions on Helicobacter pylori gastric lymphoma

By usmlevideoss

Of the following, which is the most common site for MALT lymphoma? 

A.head

B.neck

C.stomach

D.kidney

E.ski 

Correct Answer is C. The stomach is the most common site for MALT lymphoma. 

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Of the following, which is most commonly associated with gastric MALT lymphoma? 

A.Helicobacter pylori 

B.Alcohol 

C.Smoking 

D.Hepatitis B virus 

E.Epstein-Barr virus 

Correct Answer is A. Lymphoma is the second most common primary cancer of stomach, after adenocarcinomas. Almost all are non-Hodgkin lymphomas and are generally classified as B-cell mucosa-associated lymphoid tissue (MALT) lymphomas.  Helicobacter pylori (H.pylori) infection increases the risk for gastric MALT lymphoma. Over 90% of low-grade primary gastric mucosa-associated lymphoid tissue (MALT-type) lymphomas are associated with H pylori infection. Patients with primary gastric MALT-lymphoma should be tested for H pylori infection and treated if positive. Successful cure of Helicobacter pylori infection is associated with remission of gastric MALT lymphoma in most patients. 

Incorrect Answers

B.Alcohol is associated with cancer of the breast, liver, esophagus, head and neck 

C.Smoking is associated with cancer of the upper aerodigestive tract and bladder 

D.Hepatitis B virus is associated with liver cancer 

E.Epstein-Barr virus is associated with Burkitt’s lymphoma and nasal T-cell lymphoma. 

Reference: Harrison’s Principles of Internal Medicine, 21e

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