Graft-versus-host disease (GVHD)

Graft-versus-host disease (GVHD)  Graft-versus-host disease (GVHD) is a life-threatening complication that can occur after certain stem cell or bone marrow transplants.  -it is the primary cause of morbidity and mortality after hematopoietic cell transplantation  -30 to 70 percent of transplant recipients develop GVHD Time course: Acute GVHD usually happens in the first 100 days after […]

Can you answer this question?

A 3 year-old male is brought to your office for the evaluation of recurrent infections and persistent hunger, and not gaining weight. His mother reports that his medical history is significant for recurrent skin abscesses with staphylococcus aureus. Recently he started to complain about abdominal pain that starts one to two hours after a meal. […]

Granulomatosis with Polyangiitis (formerly Wegener Granulomatosis) 

Key Points  Granulomatosis with polyangiitis is a systemic necrotizing, mostly small vessel vasculitis of unknown etiology that manifests as granulomatous lesions of the upper respiratory tract, lungs and kidneys.  -Formerly known as Wegener Granulomatosis, it was renamed because of the eponymous individual’s association with Nazism  -GPA is the most common form of vasculitis to involve […]